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纪录片《长生不老》 16疯狂的结果
If you look at a naked mole rat, 一只裸克分子鼠 it's a thirty gram animal, the same size as a mouse, 重30克 和老鼠大小相同 yet it lives ten times longer than a mouse and is beating the odds. 但寿命却是老鼠的10倍 这有悖常理
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纪录片《长生不老》 17我希望一直活下去
So anti-oxidants do not hold the key to ageing, 因此抗氧化剂不是揭开衰老秘密的钥匙 though some of us will carry on taking them just in case, 虽然我们中的有些人仍然会使用它 hoping as ever for the elixir of youth. 并希望
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纪录片《长生不老》 18抵抗衰老的方法
It's just the realisation that things that go wrong 意识到很多部位的衰老 are part of a process, because I mean I'm watching mum ageing. 也是一个过程 因为我看着妈妈慢慢变老 I don't want to be older than Mum gets, really. 我不
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纪录片《长生不老》 19无法产生新的细胞
Bill's always believed there's a prime cause of ageing 比尔相信衰老是由某种主要原因导致的 and that if you look for it, you'll find it. 如果你试图寻找 也许会找到它 I knew since I was in high school that there's 从高中起
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纪录片《长生不老》 20停止衰老
Ten years ago Bill was part of the team that identified 10年前一个小组找到了对付端粒变短的物质 a natural antidote to telomere shortening that's in our bodies. 比尔也是那个研究小组的一员 It's an enzyme called telomerase.
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纪录片《长生不老》 21早衰老症的儿童
While Bill races to find a solution to 当比尔正在快马加鞭地寻找 telomere-shortening, 解决端粒缩短的方法时 there's one extraordinary condition 有种特别的现象 that was believed to demonstrate the problem of short telomeres,
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纪录片《长生不老》 22早衰症
Progeria is 早衰症确实是 a truly remarkable disease, and I think what is remarkable 一种值得注意的疾病 is the large number of parallels between 因为这种极端情况 this very extreme disease and the normal ageing process. 和正常衰
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纪录片《长生不老》 23延缓衰老
Meanwhile, Bill Andrews, still keen to get a drug 与此同时 比尔安德鲁 还是热衷于 to solve telomere-shortening, 寻找阻止端粒变短的药物 has set up his own company. 他成立了自己的公司 But just three years ago, 不过三年
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纪录片《长生不老》 24引起衰老症的原因
The drug hit the open market at 25,000 for one year's supply. 这种药上市一年 股市就达到25000点 Bill started his dad on TA 65 在父亲80大寿时 for his 80th birthday. 比尔就开始给父亲服用此药 Bill's analysed it in his own l
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纪录片《长生不老》 25破坏性蛋白质的产生
It's now been discovered that progeria 经实验发现早衰症 is caused by a mutation in a gene called lamin A. 是由一种叫核纤层蛋白A变异引起的 This leads the body to produce an abnormal protein 这种蛋白使那些患病小孩体内的
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纪录片《长生不老》 26抗衰老的机理
The cell cannot deal with 与新细胞相比 damage as well as it could when, 老细胞抵御这种损坏的能力 when it was young. 没那么强 I think that's actually almost the definition 我觉得这大概就是细胞衰老的 of cellular agein
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纪录片《长生不老》 27基因代代相传
When we imagine our older age, 每当想到我们变老的时候 a lot of us look at our parents. 我们大部分就会看向我们的父母 We know we've inherited their genes 我们遗传了他们的基因 and suspect that what's happening to them
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纪录片《长生不老》 28苍老的双手
I remember when she showed me her hand, 我记得 当她把手给我看时 I suddenly noticed that her hand was an old hand, 我突然间意识到她的手是如此的苍老 and I'd never really paid it any attention 在她生病之后 until somethin
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纪录片《长生不老》 29百岁老人的生活秘诀
Just how much of our future 我们的将来 lies in our genes 多少是由客观基因决定的 and how much in our own choices 多少是由我们主观选择决定的 is the question at the heart of a study by a scientist in New York 这才是一名纽
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纪录片《长生不老》 30犹太人做实验
The biology we're trying to under-cover 我们试着揭开生物学上的秘密 is that if we could imitate that, 如果我们能够进行效仿 then long life including 100 长命百岁 can be really terrific. 那真是太棒了 The population surro
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